Northwestern University Feinberg School of Medicine

Skin Disease Research Center

Sergey M Troyanovsky, PhD

Sergey M Troyanovsky, PhD

Professor of Dermatology and Cell and Molecular Biology

Focus of Work

Bio

Dr. Troyanovsky's research focuses on cadherin, intercellular adhesion, and signaling. Classic cadherins are critical proteins mediating cell-cell adhesion and various signaling pathways responsible for cellular proliferation, differentiation, and morphogenesis. Abnormalities in this system are causal factors in many pathologies, including cancer. The molecular mechanisms of cadherin-based adhesion, however, are largely unknown. How do cadherins establish the adhesion contact? How do they int...[Read full text]Dr. Troyanovsky's research focuses on cadherin, intercellular adhesion, and signaling. Classic cadherins are critical proteins mediating cell-cell adhesion and various signaling pathways responsible for cellular proliferation, differentiation, and morphogenesis. Abnormalities in this system are causal factors in many pathologies, including cancer. The molecular mechanisms of cadherin-based adhesion, however, are largely unknown. How do cadherins establish the adhesion contact? How do they interact with the cytoskeleton? What are the signaling pathways they control? Our laboratory's work is centered around these questions. We are currently working on the following specific projects.[Shorten text]

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Education and Certification

  • PhD: All-Union Cancer Research Center, Oncology (1981)

Contact

312-503-9275

Ward Building Room 9-031
303 E Chicago Avenue
Chicago IL 60611

Northwestern Scholars

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